4D NucleomeTechnology - Resources - Data

4D Nucleome Aims to Understand the Principles Underlying Nuclear Organization

Working to understand the principles underlying nuclear organization in space and time, the role nuclear organization plays in gene expression and cellular function, and how changes in nuclear organization affect both normal development and various diseases.

Review Latest News

4D Nucleome Aims to Improve Public Health

The 4D Nucleome (4DN) Program explores the 3D organization of the DNA in the nucleus and how the organization changes over time (the fourth dimension). Exploring the 4D organization of DNA requires developing new tools to observe differences in the organization of DNA between different cells and how the genome organization in the nucleus of a single cell changes over time.

Program Overview

Data Portal

Hosting data generated by the 4DN Network and other reference nucleomics data sets, and an open data processing and visualization tool set.

Nucleome Browser

Nucleome Browser is a multimodal, interactive data visualization and exploration platform to integrate genomic, imaging, and 3D structure data.

Internal Wiki

The 4D Nucleome Network Wiki is an internal collaboration site, accessible to 4DN investigators and members only.

Member Directory

Directory for all 4DN members allowing logged in members to manage profiles and team members' profiles, participate in the working groups, and more.

4DN Phase II Funded Research Announcements

The 3D Genome - Nature Reviews: Molecular Cell Biology

Mapping the Structure of Genomes in Space and Time

FOLLOW THE 4D NUCLEOME DATA ACROSS THE ENTIRE NETWORK

Latest 4DN News

2024 4DN Annual Meeting

SAVE THE DATE! Wyndham San Diego Bayside Hotel (San Diego, CA) December 11-13, 2024... Read more

March 18, 2024

4DN News and Announcements

Blake Nolan

4DN SUPER internship opportunity

Are you an undergraduate with an interest in #genomics and #CellBiology? Check out the 2024 4DN summer undergraduate research internship opportunity and apply to work on cutting-edge research! Applications open 12/15 and close 2/16.... Read more

December 21, 2023

4DN News and Announcements

Blake Nolan

4D Nucleome Tutorial Series #2

“Multimodal Visualization for 4DN data using Nucleome Browser and OME” October 28, 2022 8AM – 9AM PST; Virtual on Zoom.... Read more

October 21, 2022

4DN News and Announcements

Blake Nolan

Latest 4DN Publications

Nucleolus and centromere Tyramide Signal Amplification-Seq reveals variable localization of heterochromatin in different cell types

Kumar P, Gholamalamdari O, Zhang Y, Zhang L, Vertii A, van Schaik T, Peric-Hupkes D, Sasaki T, Gilbert DM, van Steensel B, Ma J, Kaufman PD, Belmont AS.... Read more

September 13, 2024

Latest 4DN Publications

YY1-controlled regulatory connectivity and transcription are influenced by the cell cycle

Lam JC, Aboreden NG, Midla SC, Wang S, Huang A, Keller CA, Giardine B, Henderson KA, Hardison RC, Zhang H, Blobel GA.... Read more

August 29, 2024

Latest 4DN Publications

Small data methods in omics: the power of one

Johnston KG, Grieco SF, Nie Q, Theis FJ, Xu X.... Read more

August 28, 2024

Latest 4DN Publications

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