4D NucleomeTechnology - Resources - Data

4D Nucleome Aims to Understand the Principles Underlying Nuclear Organization

Working to understand the principles underlying nuclear organization in space and time, the role nuclear organization plays in gene expression and cellular function, and how changes in nuclear organization affect both normal development and various diseases.

4D Nucleome Aims to Improve Public Health

The 4D Nucleome (4DN) Program explores the 3D organization of the DNA in the nucleus and how the organization changes over time (the fourth dimension). Exploring the 4D organization of DNA requires developing new tools to observe differences in the organization of DNA between different cells and how the genome organization in the nucleus of a single cell changes over time.
Program Overview

4DN Phase II Funded Research Announcements

The 3D Genome - Nature Reviews: Molecular Cell Biology

Mapping the Structure of Genomes in Space and Time

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4D Nucleome Publications

FOLLOW THE 4D NUCLEOME DATA ACROSS THE ENTIRE NETWORK
SAVE THE DATE! Wyndham San Diego Bayside Hotel (San Diego, CA) December 11-13, 2024... Read more
March 18, 2024
Blake Nolan
Are you an undergraduate with an interest in #genomics and #CellBiology? Check out the 2024 4DN summer undergraduate research internship opportunity and apply to work on cutting-edge research! Applications open 12/15 and close 2/16.... Read more
December 21, 2023
Blake Nolan
Chang L, Xie Y, Taylor B, Wang Z, Sun J, Armand EJ, Mishra S, Xu J, Tastemel M, Lie A, Gibbs ZA, Indralingam HS, Tan TM, Bejar R, Chen CC, Furnari FB, Hu M, Ren B.... Read more
October 18, 2024
McNamara HM, Solley SC, Adamson B, Chan MM, Toettcher JE.... Read more
October 2, 2024
Kumar P, Gholamalamdari O, Zhang Y, Zhang L, Vertii A, van Schaik T, Peric-Hupkes D, Sasaki T, Gilbert DM, van Steensel B, Ma J, Kaufman PD, Belmont AS.... Read more
September 13, 2024
Sen, A.; Xu, Z.; Tyndale, S.; Yasis, J.; Cho, C. Y.; Bump, R.; Chandran, S.; Luo, L.; Fu, Y.; Petersen, L. K.; Shokhirev, M.; Kuo, D. J.; McVicker, G. P.; Dixon, J. R.... Read more
October 4, 2024
Popay, T. M.; Pant, A.; Munting, F.; Black, M. E.; Haghani, N.; Dixon, J.... Read more
October 2, 2024
Kubica, J.; Korsak, S.; Clerkin, A. B.; Kouril, D.; Schirman, D.; Yadavalli, A. D.; Banecki, K.; Kadlof, M.; Busby, B.; Plewczynski, D.... Read more
October 2, 2024

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