2017 TCPA Awardees
Ten researchers received the Transformative Collaborative Project Award (TCPA) to build trans- or interdisciplinary teams that will pursue novel research or develop new tools and technologies to support the 4DN mission and further enhance international collaboration.
TCPA | Funded by National Institutes of Health
| PI Name | Institution Name | Title |
|---|---|---|
Karen Adelman (contact) Joanna Wysocka | Harvard Medical School | Elucidating the role of nascent RNA in enhancer-promoter communication and three-dimensional genome organization |
Brad Cairns (contact) Antonio Giraldez | University of Utah | Establishing the 3D chromatin architectural organization of the zebrafish embryonic genome |
Wouter de Laat (contact) Jeroen de Ridder | Hubrecht Institute, Netherlands | Multi-Contact Conformation Capture: uncovering regulatory hubs and mutually exclusive topologies |
Steve Henikoff (contact) Kamran Ahmad Jay Shendure William Noble | Fred Hutchinson Cancer Research Center | Tethered nuclease strategies for in situ mapping of 3D nuclear organization |
Nicola Neretti (contact) Anuj Srivastava Chao-Ting Wu | Brown University | Inference and Validation of Chromosomes 3D Structure via Statistical Shape Analysis of Elastic Curves Models |
Karla Neugebauer (contact) Joan Steitz | Yale University | The Cell Nucleus under Stress |
Francois Spitz (contact) Leonid Mirny Thomas Gregor | Institute Pasteur, Paris, France | Dynamic 3D folding of the mammalian genome: molecular determinants and impact on gene expression in vivo |
| Keji Zhao | National Heart, Lung, and Blood Institute | Development of TrAC-loop, a novel technique to detect genome-wide chromatin interactions |
TCPA | Funded by Canadian Institutes of Health Research
| PI Name | Institution Name | Title |
|---|---|---|
Tomi Pastinen (contact) Elin Grundberg Guillaume Bourque | McGill University | Accessing chromatin interactions by high-resolution analyses of correlated regulatory element variation |
Arturas Petronis (contact) Ting Wang | Centre for Addiction and Mental Health, Canada | Spatiotemporal dynamics of chromatin: the circadian and aging connection |